抗うつ薬による自殺関連事象は予測できるか?
Patients On Antidepressants Can Be Tested For Signs Of Suicidal Thoughts
http://www.medicalnewstoday.com/articles/185074.php
a small subset of individuals taking these drugs can actually experience a worsening of mood, and even thoughts of suicide. Now, UCLA researchers have developed a non-invasive biomarker, or indicator, that may serve as a type of early warning system. report that by using quantitative electroencephalographic (QEEG), a non-invasive measurement of electrical activity in the brain, they were able to observe a sharp reduction of activity in a specific brain region in individuals who proved susceptible to thoughts of suicide - within 48 hours of the start of treatment. shown that between 8 and 14 percent of depressed patients develop thoughts of suicide while taking the most common forms of depression drugs, known as selective serotonin reuptake inhibitors (SSRI). This study suggests, for the first time, a link between worsening suicidality and specific changes in brain function while on these medications. The drop occurred in the midline and right-frontal sections of the brain, areas known to control emotions. Importantly, changes in this biomarker did not predict worsening suicidal thoughts in the placebo-treated subjects, so the results suggestthat the biomarker specifically detected medication-related worsening only.”
QEEGとは?? NIRSみたいなものなのか? 抗うつ薬を服用して48時間以内に行えば、自殺への危険性を予測できるなんて そんなことって本当にあるのかな??
ちょっと信じられない。
— 独立行政法人国立国際医療研究センター国府台病院
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